Making use of single-molecule optical and AFM imaging and drive-spectroscopy approaches, we seek out to unravel the mechanistic elements of the construction and dynamics of chromosomes. Our research pursuits contain:
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Back in 1991, Sumio Iijima in the NEC Corporation had claimed the synthesis of carbon nanotubes. Band composition calculations suggested that these nanotubes could show metallic band conduction. This is able to be a significant gain over the conducting polymers we experienced explored, which were being, in fact, disordered semiconductors offering merely variable-range hopping conductivity.
Considering that 2000, Dekker has shifted the main emphasis of his do the job in the direction of biophysics the place he experiments the Qualities of solitary biomolecules and cells utilizing the applications of nanotechnology. This change of area was driven by his fascination for that extraordinary working of Organic molecular buildings, and from the extended-expression point of view that numerous interesting discoveries may be anticipated In this particular subject.[five] Present-day strains of research in his biophysics group are in the areas of:[6]
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Direct immobilization of native yeast iso-one cytochrome c on bare gold: speedy electron relay to redox enzymes and zeptomole protein-film voltammetry
You're a Christian. If you could possibly make this kind of artificial mobile, would you be a person step closer to God, or would the function of God have diminished fairly once again?
Atomic power microscopy displays that vaccinia topoisomerase IB generates filaments on DNA inside of a cooperative fashion
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‘The fantastically subtle way wherein things in character perform by no means ceases to amaze me. If we resolve the puzzle of how life arrived into getting, I anticipate that my amazement at the complexity of generation could have elevated and with it my awe with the greatness with the Creator.’
Tests pseudotopological and nontopological models for SMC-driven DNA loop extrusion from roadblock-traversal experiments
Lots of new phenomena have been found, and he and his investigate group founded a leading posture In this particular area of investigate. Dekker and his analysis team identified new physics of nanotubes as well as explored the feasibility of molecular electronics. In 1998, they have been the first to develop a transistor according to one nanotube molecule.
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Eventually, I'll briefly sketch many of our Thoughts to explore the developing of synthetic cells, particularly our very first measures to determine artificial mobile division.